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1. Govind, C.K., Zhang, F., Qiu, H., Hofmeyer, K., Hinnebusch, A.G. Gcn5 promotes acetylation, eviction and methylation of nucleosomes in transcribed coding regions. Mol. Cell 25: 31-42, 2007.

2. Fekete, C.A, Mitchell, S.F., Cherkasova, V.A., Applefield, D., Algire, M.A., Maag, D., Saini, A.K., Lorsch, J.R., Hinnebusch, A.G. N- and C-terminal residues of eIF1A have opposing effects on the fidelity of start codon selection. EMBO J., 26:1602-1614, 2007.

3. Cheung, Y.N., Maag, D., Mitchell, S.F., Fekete, C.A, Algire, M.A., Takacs, J.E. Shirokikh, N., Pestova, T., Lorsch, J.R., Hinnebusch, A.G. Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo. Genes Dev. 21:1217-1230, 2007.

4. Martin-Marcos, M.P., Hinnebusch, A.G., Tamame, M. Ribosomal protein L33 is required for ribosome biogenesis, subunit joining and repression of GCN4 translation. Mol. Cell. Biol., 5968-5985, 2007.

5. Wong, C.M., Qiu, H., Hu, C., Dong, J., Hinnebusch, A.G. Yeast cap binding complex (CBC) impedes recruitment of cleavage factor IA to weak termination sites. Mol. Cell. Biol., 6520-6531, 2007.

6. Jivotovskaya, A.V., Valasek, L., Hinnebusch, A.G, Nielsen, K.H. Eukaryotic Translation Initiation Factor 3 (eIF3) and eIF2 Can Promote mRNA Binding to 40S Subunits Independently of eIF4G in Yeast. Mol. Cell. Biol. 26:1355-1372, 2006.

7. Hinnebusch, A.G. eIF3: a versatile scaffold for translation initiation complexes. Trends Biochem. Sci. 31:553-562, 2006.

8. Qiu, H., Hu, C., Wong, C.M., Hinnebusch, A.G. The Spt4p subunit of yeast DSIF stimulates association of the Paf1 complex with elongating RNA polymerase II. Mol. Cell. Biol. 26:3135-48, 2006.

9. Nielsen, K.H., Valasek, L., Sykes, C., Jivotovskaya, A., Hinnebusch, A.G. Interaction of the RNP1 motif in PRT1 with HCR1 promotes 40S binding of eukaryotic initiation factor 3 in yeast. Mol. Cell. Biol. 26:2984-98, 2006.

10. Chen, Z.Q., Dong, J., Ishimura, A., Daar, I., Hinnebusch, A.G., Dean, M. The essential vertebrate ABCE1 protein interacts with eukaryotic initiation factors. J. Biol. Chem.281:7452-7, 2006.

11. Hinnebusch, A.G. Translation. Linder, P. Shore, D., Hall, M. (eds). Landmark Papers in Yeast Biology. Cold Spring Harbor Laboratory Press: NY, pp.85-108, 2006.

12. Ron, D., Hinnebusch, A.G. Targeting translation in hypoxic tumors. ACS Chem Biol. 1:145-8, 2006.

13. Hinnebusch, A.G., Dever, T.E., Asano, K.A. Mechanisms of translation Initiation in the yeast Saccharomyces cerevisiae. Cold Spring Harbor Laboratory Press: NY, pp.225-68, 2006.

14. Sattlegger, E., Hinnebusch, A.G. Polyribosome binding by GCN1 is required for full activation of eukaryotic translation initiation factor 2α kinase GCN2 during amino acid starvation. J. Biol. Chem. 280: 16514-16521, 2005.

15. Dever, T.E., Hinnebusch, A.G. GCN2 whets the appetite for amino acids. Mol Cell. 18:141-142, 2005.

16. Qiu H., Hu C., Zhang, F., Hwang G.J., Swanson, M.J., Boonchird, C., Hinnebusch, A.G. Interdependent recruitment of SAGA and Srb mediator by transcriptional activator Gcn4p. Mol Cell Biol. 25: 3461-3474, 2005.

17. Pereira, C.M., Sattlegger, E., Jiang, H.Y., Longo, B.M., Jaqueta, C.B., Hinnebusch, A.G., Wek R.C., Mello L.E., Castilho B.A. IMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activation. J. Biol. Chem. 280:28316-28323, 2005.

18. Padyana, A.K., Qiu, H., Roll-Mecak, A., Hinnebusch, A.G., Burley S.K. Structural basis for autoinhibition and mutational activation of eukaryotic initiation factor 2α protein kinase GCN2. J. Biol.Chem. 280:29289-29299, 2005.

19. Fekete, C.A., Applefield, D.J., Blakely, S.A., Shirokikh, N., Pestova, T., Lorsch, J.R., Hinnebusch, A.G. The eIF1A C-terminal domain promotes initiation complex assembly, scanning and AUG selection in vivo. EMBO J. 24:3588-3601, 2005.

20. Hinnebusch, A.G. Translational regulation of gcn4 and the general amino acid control of yeast. Annu. Rev. Microbiol. 59: 407-450, 2005.

21. Govind, C.K., Yoon, S., Qiu, H., Govind, S., Hinnebusch, A.G. Simultaneous recruitment of coactivators by Gcn4p stimulates multiple steps of transcription in vivo. Mol Cell Biol. 25:5626-5638, 2005.

22. Kim, S.J., Swanson, M.J., Qiu, H., Govind, C.K., Hinnebusch, A.G. Activator Gcn4p and Cyc8p/Tup1p are interdependent for promoter occupancy at ARG1 in vivo. Mol Cell Biol. 25:11171-11183, 2005.

23. Hinnebusch, A.G. eIF2a kinases provide a new solution to the puzzle of substrate specificity. Nat. Struct. Mol Biol.12:835-838, 2005.

24. Dong, J., Lai, R., Jennings, J.L., Link, A.J., Hinnebusch, A.G. The novel ATP-binding cassette protein ARB1 is a shuttling factor that stimulates 40S and 60S ribosome biogenesis. Mol. Cell. Biol. 25:9859-9873, 2005.

25. Nielsen, K.H., Szamecz, B., Valasek, L., Jivotovskaya, A., Shin, B., Hinnebusch, A.G. Functions of eIF3 downstream of 48S assembly impact AUG recognition and GCN4 translational control. EMBO J. 23:1166-1177, 2004.

26. Qiu, H., Hu, C., Yoon, S., Natarajan, K., Swanson, M.J., Hinnebusch, A.G. An array of coactivators is required for optimal recruitment of TATA binding protein and RNA polymerase II by promoter-bound Gcn4p. Mol.Cell.Biol. 24:4104-4117, 2004.

27. Sattlegger, E., Swanson, M.J., Ashcraft, E.A., Jennings, J.L., Fekete, R.A., Link, A.J., Hinnebusch, A.G. YIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed. J. Biol. Chem. 279: 29952-29962, 2004.

28. Kadaba, S., Krueger, A., Trice, T., Krecic, A.M., Hinnebusch, A.G., Anderson, J. Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiae. Genes Dev. 18:1227-1240, 2004.

29. Valasek, L., Nielsen, K.H., Zhang, F., Fekete, C.A., Hinnebusch, A.G. Interactions of eukaryotic translation initiation factor 3 (eIF3) subunit NIP1/c with eIF1 and eIF5 promote preinitiation complex assembly and regulate start codon selection. Mol Cell Biol.24:9437-9455, 2004.

30. Zhang, F., Sumibcay, L., Hinnebusch, A.G., Swanson, M.J. A triad of subunits from the Gal11/tail domain of Srb mediator is an in vivo target of transcriptional activator Gcn4p. Mol. Cell. Biol. 24:6871-6886, 2004.

31. Dong, J., Lai, R., Nielsen, K., Fekete, C.A., Qiu, H., Hinnebusch, A.G. The essential ATP-binding cassette protein RLI1 functions in translation by promoting preinitiation complex assembly. J. Biol. Chem. 279: 42157-42168, 2004.

32. Yoon, S., Govind, C.K., Qiu, H., Kim, S.J., Dong, J., Hinnebusch, A.G. Recruitment of the ArgR/Mcm1p repressor is stimulated by the activator Gcn4p: a self-checking activation mechanism. Proc Natl. Acad. Sci. 101:11713-11718, 2004.

 

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